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Scientist I/II, Bioassay Development, Analytical Development and Quali

Company: AbbVie
Location: Redwood City
Posted on: May 20, 2019

Job Description:

Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica--, Venclexta---, and Empliciti--- and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer.AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. AbbVie is also expanding their expertise through partnering with companies leading the way in emerging biologic technologies including oncolytic virus' and CAR-T cells.We are seeking a Bioassay Development Scientist to join our Bioassay Development team within the Analytical Development group. In this lab-based position you will contribute to the functional characterization of new oncology drugs in development. As part of our team, your major responsibilities will include binding /bioassay method development/optimization/troubleshooting, sample testing, and collaborating with the Analytical Development team on molecular characterization to support the development of therapeutic antibodies, antibody variants, and antibody drug conjugates.Scientist I: Bachelor's Degree in biology, biochemistry, or a related field (or equivalent education) with typically 5 years of experience, or Master's Degree in biology, biochemistry, or a related field (or equivalent education) with typically 2 years of experience.Scientist II: Bachelor's Degree in biology, biochemistry, or a related field (or equivalent education) with typically 7 years of experience, or Master's Degree in biology, biochemistry, or a related field (or equivalent education) with typically 5 years of experience.

  • Experience performing target binding and biological activity assays in a Bioassay Development group or QC lab setting within a Chemistry Manufacturing and Controls (CMC) organization.
  • Demonstrated proficiency with mammalian cell culture and cell-based functional assays is desirable.
  • Strong working knowledge and hands-on experience with technologies and methodologies such as ELISA, TR-FRET, AlphaScreen, Octet, and/or other binding assay platforms.
  • Proven ability to work in a highly collaborative scientific environment with strong verbal and written communication skills.
  • The ideal candidate will be hard-working, self-motivated, detail-oriented, highly organized, and can learn and adapt quickly.

Keywords: AbbVie, San Francisco , Scientist I/II, Bioassay Development, Analytical Development and Quali, Other , Redwood City, California

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