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Scientist I, Pharmacology

Company: AbbVie
Location: Redwood City
Posted on: March 18, 2019

Job Description:

Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica--, Venclexta---, and Empliciti--- and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. AbbVie is also expanding their expertise through partnering with companies leading the way in emerging biologic technologies including oncolytic virus' and CAR-T cells. This position is based at AbbVie in the Redwood City, CA location. We are looking for a highly motivated laboratory scientist to develop and evaluate biomarker and diagnostic strategies in support of the discovery, development and commercialization of novel therapies in immunology and immune oncology. The scientist will be responsible for assisting in the design and in performing complex laboratory investigations involving primary cell culture and Flow Cytometry (FACS) to identify biomarkers of efficacy/safety of development stage. While performing the duties the experience will provide a foundation in the discovery, characterization, clinical validation and utilization of innovative biomarkers and potential diagnostics in the drug development setting. The scientist would be expected to work collaboratively, under the supervision of experienced biomarker scientists. Core Job Responsibilities:

  • The scientist will perform experiments involving use of animal blood, staining with fluorescently labeled antibodies and FACS.
  • Independent laboratory investigations by the scientist will directly support the development the validation of clinically applicable biomarker assays (including pharmacodynamic, predictive, prognostic, safety and other biomarkers).
  • The scientist must demonstrate proficiency analyzing and critiquing results, trouble-shooting experiments, drafting experimental protocols while designing, implementing and overseeing biomarker and data analysis
  • The scientist must understand and adhere to corporate standards regarding code of conduct or operating procedures and maintain accurate records according to AbbVie policies.
    • Bachelor's Degree Chemistry, Biology, or related field or equivalent education with typically 5 years of experience, or Master's Degree or equivalent education with typically two years of experience.
    • Ability to learn and share knowledge with colleagues. Good oral and written communication skills. Actions demonstrate that group/project success benefit everyone.
    • Demonstrated ability to work independently when generating precise, reliable, reproducible laboratory results.
    • Ability to follow operating procedures accurately and, when appropriate, optimize procedures to enhance productivity and efficiency. Equal Opportunity Employer Minorities/Women/Veterans/Disabled

      Keywords: AbbVie, San Francisco , Scientist I, Pharmacology, Other , Redwood City, California

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