Computational Life Science Research Professional 1

Company: Stanford Medicine
Location: San Gregorio
Posted on: May 15, 2022

Job Description:

Stanford University is seeking a Computational Life Science Research Professional 1 to perform bioinformatic analysis in defined research projects, and independently design and analyze computational workflows. Work will be conducted in a laboratory whose primary focus is the discovery of cellular signaling mechanisms that serve as a basis for developing novel therapeutic approaches for Alzheimer's disease, Huntington's disease and other neurological disorders. The LSRP will be primarily responsible for analyzing experimental data, and assisting in behavior testing and pathological analysis of various mouse models of neurodegenerative diseases. The LSRP will independently run analyses after consultation with a supervisor and will help modify existing pipelines and procedures, collaborating with experimenters on the appropriate analysis of generated data. The LSRP will be responsible for a variety of computational and statistical tasks. The LSRP will also be responsible for maintaining detailed and reproducible documentation and will provide technical support and training to other laboratory personnel.

Duties include:

• Independently conduct analyses, maintaining detailed documentation of code suitable for publication.
• Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to analytical design in collaboration with senior researcher.
• Review literature on an ongoing basis to remain current with new software and apply learnings to related research.
• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
• Assist with orientation and training of new staff or students on lab procedures or techniques.
  *- Other duties may also be assigned
  
  DESIRED QUALIFICATIONS:
  
  • Prefer a degree in Bioinformatics, or Biological Sciences with evident computing experience.
  • Strong Linux system familiarity, high performance computing (HPC) experience preferred
  • Fluency in either R or python, familiarity with both as well as shell scripting
  • Previous experience with NGS datasets, particularly gene expression analysis (RNAseq, sc/snRNAseq)
  • Familiarity with common bioinformatics tools (plink, bcftools/samtools, GATK, DESeq2)
  • Raw genetic data quality control, annotation and analysis experience preferred
  • Ability to troubleshoot & develop workflows with strong documentation.
  • Previous experience in genomics or neuroscience is desirable.
    
    EDUCATION & EXPERIENCE (REQUIRED):
    
    Bachelor's degree in related scientific field.
    
    KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
    
    • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
    • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
    • Ability to maintain detailed records of experiments and outcomes.
    • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
    • Ability to work under deadlines with general guidance.
    • Excellent organizational skills and demonstrated ability to accurately complete detailed work.
      
      PHYSICAL REQUIREMENTS*:
      
      • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
      • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
      • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
      • Must have correctible vision to perform duties of the job.
      • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
      • Ability to lift heavy objects weighing up to 50 pounds.
      • Ability to work in a dusty, dirty, and odorous environment.
      • Position may require repetitive motion and extended time sitting at a computer.
        *- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
        
        WORKING CONDITIONS:
        
        • May require working in close proximity to blood borne pathogens.
        • May require work in an environment where animals are used for teaching and research.
        • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
        • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
        • May require extended or unusual work hours based on research requirements and business needs.
          
          WORK STANDARDS:
          
          • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
          • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
          • Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu .
            
            As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit https://cardinalatwork.stanford.edu/working-stanford/covid-19/interim-policies/covid-19-surveillance-testing-policy
            
            Additional Information
            
            • Schedule: Full-time
            • Job Code: 4945
            • Employee Status: Regular
            • Pay Grade: E
            • Department URL: http://med.stanford.edu/neurology/
            • Requisition ID: 93851 As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit https://cardinalatwork.stanford.edu/working-stanford/covid-19/interim-policies/covid-19-surveillance-testing-policy

Keywords: Stanford Medicine, San Francisco , Computational Life Science Research Professional 1, Other , San Gregorio, California