Senior Scientist, Directed Evolution

Company: Kelly
Location: Pleasant Hill
Posted on: May 15, 2022

Job Description:

Kelly Science and Clinical is the world's most recognized brand in science and clinical staffing with more than 100 locations in North America, Europe, and the Pacific Rim. Our scientists contribute to the research and development of the next generation of small molecule drugs, biologics and cellular therapies. Overview We are seeking a Senior Scientist, Directed Evolution for one our clients, a start-up biotechnology company in Berkeley, CA that is developing a massively parallel, single-molecule protein sequencing platform that will transform proteomics and usher in a new era of insights into human biology and disease. The successful candidate will possess a PhD in bioengineering, computational biology, or related fields with an emphasis on protein structure and function. Previous experience with high-throughput experimentation and laboratory automation is preferred. Responsibilities

• Developing experimental and computational methods to discover and reprogram enzyme target specificity or protein binding affinity.
• Screening and maturing protein variants using experimental methods such as PACE, phage-display, yeast-display, or other evolution methodologies.
• Designing and developing automated high-throughput laboratory pipelines. Analyzing high-throughput data to drive experimentation. Qualifications
  • PhD in bioengineering, computational biology, or related field. Needs to be interest in working outside of one specialties: in-depth molecular biology experience: cloning, protein purification, next generation sequencing, qPCR, etc.
  • Ideal experience with evolving enzymes for enhanced specificity and/or specificity reprogramming.
  • Experience building high-throughput automated experimental pipelines. Experience in data-driven quantitative biology.
  • Of interest, but not necessary: ability to design quantitative protocols for use in machine learning or similar data-driven feedback mechanisms.
  • Experience with molecular visualization software such as PyMOL or similar is preferred. Team player with excellent verbal and written communication skills.
  • Previous experience managing either RAs or undergraduates You should know: Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process. Why Kelly - ? Kelly - Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interests-it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed. About Kelly - At Kelly, we're always thinking about what's next and advising job seekers on new ways of working to reach their full potential. In fact, we're a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world. Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. ]]

Keywords: Kelly, San Francisco , Senior Scientist, Directed Evolution, Other , Pleasant Hill, California