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Life Science Rsch Prof 1

Company: Stanford Medicine
Location: Stanford
Posted on: January 16, 2022

Job Description:

Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments .

About the Lab

In the lab of Dr. Le Cong at Stanford (Dept. of Pathology and Dept. of Genetics, Wu-Tsai Neuroscience Institute and Stanford Bio-X Institute), the overarching goal is to develop cutting-edge gene-editing and single-cell technology to understand complex diseases, paving the way for precision gene therapies. We integrate machine learning (ML) and computational tools, and apply the technologies to disease-relevant models. Some ongoing examples are: using state-of-the-art CRISPR screens to understand neuro-immunology in stem cell models; developing single-cell tools to study disease-driving mutations in patient samples of Alzheimer's Diseases. In our interdisciplinary team, we pioneered gene-editing and epigenetics tools, high-throughput CRISPR screening, and single-cell computational analysis approaches. Please see more at our lab website:

Recent work include:

-New Gene-editing Technology

(Nucleic Acid Research 2021, Molecular Therapy 2020, JACS 2019)

-Single-cell and Systems Biology

(ICML 2020, Cell Reports 2019, Cell 2017)

-Stem Cell and Disease Modeling

(Trends in Genetics 2021, Cancer Discovery 2020)

We are a highly innovative team collaborating with expert groups in immunology, stem cell biology, and neuroscience. This will be a unique opportunity to learn and grow in research, biotechnology development, and translational applications.

About the Job

We are looking for highly motivated individuals to join our laboratory to perform technology-driven research in a dynamic and exciting environment. A successful candidate will work independently and collaborate with lab members to engage in developing gene-editing and single-cell genomics tools, and apply them to study neuro-degenerative diseases with stem cell and patient-derived models. The candidate will execute bench (wet lab) experiments focusing on protein engineering, next-generation sequencing, and cell culture. The candidate will also be responsible for some basic lab operations. There will also be opportunities for computational skills development, such as bioinformatics analysis. This position offers a rich opportunity to engage research at the frontier of biotech fields, aiming for next stage of your career, either in academic or industry.

Duties include:

  • Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
  • Independently conduct experiments; maintain detailed records of experiments and outcomes.
  • Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
  • Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
  • Contribute to publication of findings as needed. Participate in the preparation of written documents.
  • Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
  • Assist with orientation and training of new staff or students on lab procedures or techniques.

    *- Other duties may also be assigned

    • Bachelor's degree life sciences or a related area.
    • Knowledge and experience in any of the following fields: molecular biology, cell biology, genomics, or related biology and bio-engineering fields.
    • Good organizational skills, lab notebook practices, and attention to detail.
    • Self-motivated, good communications and the ability to perform as part of a team.


      Bachelor's degree in related scientific field.

      • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
      • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
      • Ability to maintain detailed records of experiments and outcomes.
      • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
      • Ability to work under deadlines with general guidance.
      • Excellent organizational skills and demonstrated ability to accurately complete detailed work.



        • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
        • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
        • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
        • Must have correctible vision to perform duties of the job.
        • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
        • Ability to lift heavy objects weighing up to 50 pounds.
        • Ability to work in a dusty, dirty, and odorous environment.
        • Position may require repetitive motion.

          *- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

          • May require working in close proximity to blood borne pathogens.
          • May require work in an environment where animals are used for teaching and research.
          • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
          • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
          • May require extended or unusual work hours based on research requirements and business needs.

            Additional Information
            • Schedule: Full-time
            • Job Code: 4945
            • Employee Status: Regular
            • Pay Grade: E
            • Requisition ID: 91464 As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit

Keywords: Stanford Medicine, San Francisco , Life Science Rsch Prof 1, Other , Stanford, California

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