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Staff Research Associate I - UCSF Liver Center

Company: UCSF Medical Center
Location: San Francisco
Posted on: November 22, 2021

Job Description:

Job Summary

The UCSF Liver Center ( operates several core facilities as part of its mission to support liver-related research programs at UCSF. The Staff Research Associate I (SRA I) will isolate primary cells from rodent and human livers within the Liver Cell Isolation, Analysis and Immunology Core. The SRA I will implement established protocols for cell isolation liver by perfusion digestion of the intact liver. The SRA I will then purify crude cell suspensions by a range of techniques from MACS to centrifugal elutriation, and prepare final preparations as suspensions or primary cultures. The work involves manual skill, attention to detail, and the ability to manage a schedule with multiple clients.

Additional duties include expansion, banking and distribution of select liver cell lines used by UCSF researchers as well as maintenance of iPS cell lines as needed. To ensure smooth operation of the core facility, the SRA I will prepare and sterilize all instruments and solutions required for cell isolation and culture; maintain all relevant equipment (perfusion pumps, centrifuges, rotors, incubators, biosafety cabinets); order and receive supplies; maintain accurate records of completed work; keep up-to-date records of the cost of all work for recharge accounting; and assist with/stewardship of relevant IACUC and CHR protocols. The SRA I must be willing to work periodic weekends to maintain active cell cultures, as well as occasional nights often with short notice to accommodate the unplanned receipt of human liver tissue.

Department Description

Research in gastrointestinal and liver diseases is active in the UCSF Division of Gastroenterology (GI). The division has a longstanding reputation for excellence in hepatology research and has a growing investigative program in luminal gastroenterology. Faculty in the Division of Gastroenterology contribute to discovery in several areas, ranging from the identification of basic mechanisms of GI disease, to the improvement of outcomes following liver transplantation, to the optimization of GI care in resource-poor settings. The division also provides comprehensive training in GI research through its postdoctoral programs.

Required Qualifications

--- BA/BS degree in a biological science or equivalent education, or experience with the basic techniques or methods required by the position; or an equivalent combination of education and experience
--- Demonstrated knowledge of chemistry, sufficient to prepare and pH laboratory solutions
--- Working knowledge of Microsoft Excel
--- Demonstrated record of excellent attendance and punctuality

Note: Physical/health screening required.

Preferred Qualifications

--- Experience with small animal surgery and anesthesia
--- Knowledge of sterile technique
--- Knowledge of cell culture (changing medium, cell passaging)
--- Knowledge of cell isolation methods including differential centrifugation and MACS, and possibly FACS

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Keywords: UCSF Medical Center, San Francisco , Staff Research Associate I - UCSF Liver Center, Other , San Francisco, California

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