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Senior Scientist, Assay Development

Company: Berkeley Lights, Inc.
Location: Emeryville
Posted on: February 25, 2021

Job Description:

Here at Berkeley Lights, we think cells are awesome! Cells are capable of manufacturing cures for diseases, fibers for clothing, energy in the form of biofuels, and food proteins for nutrition. So the question is, if nature is capable of manufacturing the products we need in a scalable way, why aren't we doing more of this? Well, the answer is that with the solutions available today, it is hard. It takes a long time to find the right cell for a specific job, costs lots of money, and if you have picked a suboptimal cell line, has a very low process yield. Berkeley Lights has the complete solution to find the best cells by functionally screening and recovering individual cells for antibody discovery, cell line development, T cell analysis, and synthetic biology. Our proprietary technology and Beacon-- and LightningTM--systems accelerate the rate researchers can discover and develop cell-based products in a fraction of the time and at a fraction of the cost of conventional, legacy research methods. Using our tools and solutions, scientists can find the best cells, the first time they look. Our goal is to continue to collaborate with customers to drive the adoption of our technologies, making cell-based products and therapeutics more easily accessible the world over! You will play a major role here and our success depends on you! We have been changing how the world develops cell-based products since 2011, and now our family of around 200 employees welcomes you to consider joining us on this incredible journey. We are seeking an exceptional candidate for the position of Sr Scientist, Assay Development to join an interdisciplinary product development team at the company's headquarters in Emeryville, CA. This talented biologist will join our Life Sciences R&D team to work in collaboration with instrument and software engineers as we scale down biology workflows to the single cell level using our platforms to achieve high throughput, automated solutions for assay development. The candidate will work closely with our research and applications development teams to build upon our current capabilities and transition biology workflows to the nanoscale. The ideal candidate is an experienced molecular biologist with strong troubleshooting skills at the bench where you'll be working with new reagents, assays and protocols with the goal of helping develop them for the best customer experience possible. Responsibilities

  • Work within the R&D team to develop new reagents and protocols into finished products for our customers
  • Troubleshoot molecular biology workflows to improve yield, quality and reproducibility.--
  • Optimization and QC of molecular biology reagent formulations, kits and customer facing protocols for use at the bench or in a microfluidic environment--
  • Work with a large variety of molecular and cellular biology reagents and tools to guide product development (NGS, Cloning, Buffers, Cell Culture)
  • Transfers kits and protocols from the R&D team to our field and applications support groups.
  • Quickly develop expertise in new areas of study through reading primary literature
  • Work closely with a diverse team of biologists, bioinformaticians, engineers and other scientists to adapt and invent new assays and workflows
  • Present data internally to development teams, management and executives to inform and drive new product development Required Qualifications
    • Ph.D. in molecular biology, cell biology, genetics or a related field with 2+ years of additional experience in developing reagents or kits in an industry setting
    • Experienced in optimizing protocols, reagents or kits for customer facing products
    • Strong hands-on experience with molecular biology methodologies, RT-PCR, DNA/RNA isolation, NGS library preparation including RNA-seq and/or DNA-seq, DNA cloning and vector construction.
    • Experienced with analyzing and interpreting data from NGS experiments to generate actionable conclusions
    • Familiarity with cell/tissue culture, cell-based assays, transfection, protein expression and microscopy platforms
    • Excellent collaboration, interpersonal, and communication skills to clearly articulate ideas, problems, and solutions.
    • Ability to go "off-protocol" and invent, optimize and develop new approaches.--
    • Skilled problem solver with the ability to quickly identify root cause and corrective action
    • Comfortable learning and working with new technology and helping provide solutions outside of your area of expertise--
    • A working knowledge of antibody discovery, antibody therapeutics or cell line development
    • Quickly learn new concepts and protocols from primary literature and develop new expertise in a short amount of time
    • Ability to work in high pace environment, with rapid experimental design iterations and short timelines
    • A team first attitude and ability to function well in a matrixed organization
    • Proficient data analysis skills; experience with data-mining software (e.g. Tableau, Spotfire) is desired. The California Consumer Privacy Act (CCPA) is effective January 1, 2020. Please read our--California Consumer Privacy Act Disclosure Form --regarding the CCPA and Berkeley Lights' required disclosures about the collection of personal information.

Keywords: Berkeley Lights, Inc., San Francisco , Senior Scientist, Assay Development, Other , Emeryville, California

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