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Associate Scientist, DMPK-Bioanalysis

Company: GENENTECH
Location: San Francisco
Posted on: January 15, 2021

Job Description:

The PositionThe DMPK department is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the mechanisms of absorption, distribution, metabolism, and excretion of small molecule drug candidates. We accomplish our goals through the application of state-of-the-art technologies for bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK department works in close partnership with disciplines such as medicinal chemistry, in vivo pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize lead compounds, select clinical candidates, conduct preclinical studies, support clinical development and contribute to IND and NDA filings.The individual will be involved in the following activities as part of their role:Develop new bioanalytical methods to support new modality drug discoveryImplement new technology platforms and novel tools for DMPK challenges; develop sample preparation, chromatographic separation techniques; data analysis and interpretation; maintain current knowledge of latest bioanalytical methods and technologiesOversee discovery bioanalytical activities conducted at contract research laboratories (CROs)Participate and present in cross-functional project teams, manage multiple projects within timelines according to high scientific and ethical standards.Qualifications:The candidate for the DMPK-Bioanalytical Associate Scientist position must have a doctoral degree in analytical chemistry, biochemistry, pharmaceutical science or equivalent with 0-3 years relevant industry experience that focused on mass spectrometry analysis of small molecules, peptides, nucleic acids, proteins or glycans.In-depth bioanalytical knowledge and experience with LC-MS/MS is required; experience with AB Sciex triple quadruple or Thermo Orbitrap is a plus.The candidate needs to possess a demonstrated ability to work independently in a fast-paced environment, as well as in a team setting.The candidate should have basic understanding of pharmacokinetics and drug metabolism principles.The candidate should have excellent organizational and communication skills.Who We AreGenentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We're focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.The next step is yours. To apply today, click on the "Apply for this job" button.Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page . Job Facts JOB FUNCTIONResearch & Early Development COMPANY/DIVISIONPharmaceuticals SCHEDULEFull time JOB TYPERegular

Keywords: GENENTECH, San Francisco , Associate Scientist, DMPK-Bioanalysis, Other , San Francisco, California

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