Associate Scientist, DMPK-Bioanalysis
Company: GENENTECH
Location: San Francisco
Posted on: January 15, 2021
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Job Description:
The PositionThe DMPK department is dedicated to enabling the
discovery, development and commercialization of safe and effective
medicines by elucidating the mechanisms of absorption,
distribution, metabolism, and excretion of small molecule drug
candidates. We accomplish our goals through the application of
state-of-the-art technologies for bioanalysis, drug metabolism,
drug transport and pharmacokinetics. The DMPK department works in
close partnership with disciplines such as medicinal chemistry, in
vivo pharmacology, toxicology, pharmaceutical sciences, clinical
pharmacology and regulatory to optimize lead compounds, select
clinical candidates, conduct preclinical studies, support clinical
development and contribute to IND and NDA filings.The individual
will be involved in the following activities as part of their
role:Develop new bioanalytical methods to support new modality drug
discoveryImplement new technology platforms and novel tools for
DMPK challenges; develop sample preparation, chromatographic
separation techniques; data analysis and interpretation; maintain
current knowledge of latest bioanalytical methods and
technologiesOversee discovery bioanalytical activities conducted at
contract research laboratories (CROs)Participate and present in
cross-functional project teams, manage multiple projects within
timelines according to high scientific and ethical
standards.Qualifications:The candidate for the DMPK-Bioanalytical
Associate Scientist position must have a doctoral degree in
analytical chemistry, biochemistry, pharmaceutical science or
equivalent with 0-3 years relevant industry experience that focused
on mass spectrometry analysis of small molecules, peptides, nucleic
acids, proteins or glycans.In-depth bioanalytical knowledge and
experience with LC-MS/MS is required; experience with AB Sciex
triple quadruple or Thermo Orbitrap is a plus.The candidate needs
to possess a demonstrated ability to work independently in a
fast-paced environment, as well as in a team setting.The candidate
should have basic understanding of pharmacokinetics and drug
metabolism principles.The candidate should have excellent
organizational and communication skills.Who We AreGenentech, a
member of the Roche group and founder of the biotechnology
industry, is dedicated to pursuing groundbreaking science to
discover and develop medicines for people with serious and
life-threatening diseases. To solve the world's most complex health
challenges, we ask bigger questions that challenge our industry and
the boundaries of science to transform society. Our
transformational discoveries include the first targeted antibody
for cancer and the first medicine for primary progressive multiple
sclerosis.Diversity and Inclusion (D&I) are critical to the
success of our company and our impact on society. We believe that
by championing diversity of background, thought and experience, we
can foster a sense of belonging and provide an environment where
every employee feels valued, included, and able to contribute their
best for the patients we serve. We're focused on attracting,
retaining, developing and advancing our people to their full
potential by rewarding bold ways of thinking and integrating
inclusive behaviors into every aspect of our work.The next step is
yours. To apply today, click on the "Apply for this job"
button.Genentech is an equal opportunity employer & prohibits
unlawful discrimination based on race, color, religion, gender,
sexual orientation, gender identity/expression, national
origin/ancestry, age, disability, marital & veteran status. For
more information about equal employment opportunity, visit our
Genentech Careers page . Job Facts JOB FUNCTIONResearch & Early
Development COMPANY/DIVISIONPharmaceuticals SCHEDULEFull time JOB
TYPERegular
Keywords: GENENTECH, San Francisco , Associate Scientist, DMPK-Bioanalysis, Other , San Francisco, California
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