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Postdoctoral Research Scholar - Newman lab

Company: Buck Institute
Location: Novato
Posted on: October 12, 2018

Job Description:

Position Summary The Newman lab studies how signaling metabolites regulate mechanisms of aging. We seek motivated, creative scientists to carry out projects that span biochemistry to translational applications in a vibrant atmosphere with a physician-scientist mentor. Position Description We focus on how mechanisms of aging are regulated by the ketone body beta-hydroxybutyrate, which is made by the body during fasting, ketogenic diet, and exercise. We use a toolkit of ketone body compounds, diet interventions, and genetic modifications to understand the mechanistic effects of ketone bodies on memory and other phenotypes in normal aging, Alzheimer's disease models, and delirium models. This work involves a combination of in vitro biochemistry, gene expression and protein analysis, and physiological and behavioral studies in laboratory mice. Qualifications * MD and/or PhD in Biology, Chemistry, or related fields * Strong bench laboratory skills * Works well in collaborative teams * Able to successfully manage an independent research project * Prior experience with mouse husbandry, transgenic mice, and behavioral testing a plus * Prior experience with PCR, RNAseq, Western blotting, mass spectrometry proteomics and metabolomics, and/or gene editing a plus About the Buck Institute At the Buck, we're big fans of life. The Buck Institute (www.buckinstitute.org) was the pioneer and is now the global leader in health span research. We believe it's possible for people to enjoy life as much at 91 as they do at 21, and to achieve that, we're seeking a more comprehensive understanding of the biology of aging itself. By exploring all possible scientific paths toward discovering and changing the ways in which we age, we believe we can achieve a day when aging no longer increases our risk for degenerative disease and help increase the number of healthy years people enjoy within their lifetime. Since 1999, we've succeeded in our mission by bringing the most capable and most passionate scientific minds together from a spectrum of disciplines. We firmly believe our work will ultimately transform the practice of medicine and help people get more life out of their lives. To Apply Please apply online by submitting 1) your CV, 2) a cover letter with a brief statement of your interests and goals, and 3) contact information for 2-3 references who are familiar with your scientific work. A brief letter of support from your PhD or prior postdoctoral adviser is desirable. For more information, please contact Thelma Garc?a, PhD at tgarcia@buckinstitute.orgSDL2017

Keywords: Buck Institute, San Francisco , Postdoctoral Research Scholar - Newman lab, Healthcare , Novato, California

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