Research Associate / Senior Research Associate - Cell Therapy

Company: Serotiny
Location: San Francisco
Posted on: May 27, 2023

Job Description:

Research Associate / Senior Research Associate - Cell Therapy Serotiny invents multi-domain proteins for gene and cell therapies including genome editors, and chimeric antigen receptors. These novel synthetic proteins are central to cutting edge therapeutics, providing enhanced safety and efficacy through advanced control methods and engineered functionalities. We strategically couple synthetic biology with data science and machine learning to generate large-scale protein libraries for high-throughput screening and analysis.Serotiny is looking for a RA/SRA who is excited to work closely with a team of protein engineers and cell biologists to build out and deploy Serotiny's high-throughput methods to characterize and develop cutting edge therapies. The position will contribute towards the development of a novel platform to generate and characterize CAR immune cells for solid tumor indications. Role

• Execute cell therapy projects with supervision from senior team members
• Conduct hands-on laboratory work to evaluate Serotiny's clonal constructs in primary cells using a variety of in vitro assays
• Manufacture genetically engineered immune cells and evaluate cell function in vitro
• Perform downstream functional assays including cytotoxicity and proliferation assays
• Run multicolor flow cytometry panels to interrogate immune cell phenotypes
• Analyze data and present results to team members and group leaders
• Maintain outstanding electronic lab notebook records
• Participate in team meetings and provide regular oral and written communication on all projects and milestonesQualifications
  • Degree in molecular biology, cell biology, immunology, biotechnology or related area
    • Research Associate: BSc. with 0-3 years of laboratory experience, or MSc.
    • Sr. Research Associate: BSc. with > 4 years of laboratory experience, or MSc. with > 2 years
    • Proficiency with culturing mammalian cells, both primary and immortalized
    • Familiarity with cell therapy workflows: primary cell isolation, activation, transduction, and cryopreservation
    • Familiarity with immunostaining methods, flow cytometry, and ELISA is a plus
    • Experience using data analysis tools such as FlowJo and GraphPad Prism is a plus
    • Excellent organizational skills, detail oriented, and an ability to prioritize effectively to deliver results within reasonably established timelines
    • Outstanding verbal and written communication skills
    • Comfortable to work in a fast-paced startup environment and able to adjust workload based upon changing priorities
    • Candidates must be authorized to work in the USPerks
      • Full health benefits
      • 401(k) with employer match Contact us We want to hear from you if you think you are meant to be at Serotiny regardless of our current available positions. Let us know if you want to help us engineer the next generation of cell and gene therapies. Full name * Email * Message * Security question * 5 + 9 = serotiny
        • 329 Oyster Point Boulevard, 3rd Floor
        • South San Francisco, CA 94080
        • info@serotiny.com - Copyright 2023 Serotiny.

Keywords: Serotiny, San Francisco , Research Associate / Senior Research Associate - Cell Therapy, Healthcare , San Francisco, California