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Life Science Research Professional 4 - Corsello Lab

Company: Stanford School of Medicine
Location: Stanford
Posted on: May 17, 2022

Job Description:

Life Science Research Professional 4 - Corsello Lab

Situated in a highly dynamic research environment within Stanford University School of Medicine and the Stanford Cancer Institute, Prof. Steven Corsello's laboratory is seeking a highly motivated Life Science Research Professional 4. The Corsello Laboratory operates at the intersection of chemical biology and functional genomics to discover novel targeted therapeutic strategies for cancer. This position affords the unique opportunity to participate in translation of basic science discoveries into therapeutic opportunities. The successful candidate will be expected to independently design and carry out experiments using diverse molecular, cellular, and biochemical techniques to address biological questions concerning, for example, compound mechanism of action or mechanisms of resistance. The LSRP4 will play a key role in developing technologies and capabilities including the execution of genome-scale CRISPR/Cas9 drug modifier screens. Candidates should have established expertise in cancer biology, as demonstrated by a track record of high impact publications. Candidates will also be expected to collaborate and communicate effectively with a multidisciplinary team.

Duties include:

  • Lead multidisciplinary teams across different faculties or schools.
  • Design research approaches for the entire project, including background research, experimental design and execution, problem solving, and writing up for publication.
  • Conduct complex (lab and/or field) experiments, and maintain detailed records of experiments and outcomes; analyze and interpret research data resulting from original procedures and methods; oversee critical analyses of data from entire project.
  • Develop new protocols; test and evaluate a variety of approaches.
  • Participate in creating new research proposals, and prepare for submission for funding and grants.
  • Prepare periodic progress reports or written reports on all phases of the research project.
  • Contribute original ideas of major methodologies that alter the course of the investigation or develop innovative solution(s) to complex research problems.
  • Perform ongoing literature review to remain current with new procedures and related research; proceed without consultation with principal investigator to implement new techniques into research project.
  • Co-author publications; may present ongoing work and findings to colleagues at academic conferences.
  • Work with health and safety department to ensure lab complies with regulations and all required trainings.
  • Supervise other staff, including hiring, performance management, and related duties. Provide instruction on complex techniques and direction on projects.
    * - Other duties may also be assigned

    DESIRED QUALIFICATIONS:
    • Experience with cell culture and gene manipulation techniques
    • Experience with general laboratory techniques including molecular cloning, western blotting, qPCR, and flow cytometry
    • Experience with pooled genetic screens in mammalian cells

      EDUCATION & EXPERIENCE (REQUIRED):

      Bachelor's degree in related scientific field and six years of relevant work experience; or Master's degree in a related scientific field and four years relevant experience; or PhD in related scientific field and two years of relevant experience.

      KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
      • Extensive understanding of scientific principles.
      • Expert level knowledge and skills in field of science related to research project.
      • General computer skills, experience with databases and scientific applications, and ability to quickly learn and master computer programs.
      • Strong analytical skills and excellent judgment.
      • Ability to work under deadlines is essential.
      • Excellent organizational skills and demonstrated ability to complete detailed work accurately.
      • Strong project management and leadership skills.

        PHYSICAL REQUIREMENTS*:
        • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
        • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
        • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
        • Must have correctible vision to perform duties of the job.
        • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
        • Ability to lift heavy objects weighing up to 50 pounds.
        • Ability to work in a dusty, dirty, and odorous environment.
        • Position may require repetitive motion.
          * - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

          WORKING CONDITIONS:
          • May require working in close proximity to blood borne pathogens.
          • May require work in an environment where animals are used for teaching and research.
          • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
          • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
          • May require extended or unusual work hours based on research requirements and business needs.

            WORK STANDARDS:
            • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
            • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned.
            • Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu .

              As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit https://cardinalatwork.stanford.edu/working-stanford/covid-19/interim-policies/covid-19-surveillance-testing-policy

              Additional Information
              • Schedule: Full-time
              • Job Code: 4954
              • Employee Status: Regular
              • Grade: I
              • Requisition ID: 93303 As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit https://cardinalatwork.stanford.edu/working-stanford/covid-19/interim-policies/covid-19-surveillance-testing-policy

Keywords: Stanford School of Medicine, San Francisco , Life Science Research Professional 4 - Corsello Lab, Healthcare , Stanford, California

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