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AstraZeneca: Cell Therapy Bioanalytical & Biomarker Scientist

Company: AstraZeneca
Location: San Francisco
Posted on: November 24, 2020

Job Description:

The Integrated BioAnalysis (iBA) group within the Clinical Pharmacology and Quantitative Pharmacology department at AstraZeneca seeks an experienced Senior Scientist or Associate Principal Scientist (level commensurate with experience) to develop, qualify and implement bioanalytical and biomarker assays for cellular therapy programs in South San Francisco, CA.The ideal candidate will have experience in the cell therapy area with extensive knowledge and experience in development of molecular-based assays to monitor cellular products.Major Duties and ResponsibilitiesServe as an expert in monitoring, quantifying and/or characterizing cell therapy products in biological matrices at the pre-clinical and clinical development stages Lead development, validation and implementation of molecular-based bioanalytical & /or biomarker assays formultiple AZ cell therapy programsContribute to bioanalytical strategies for cell therapy programs at pre-clinical and clinical development stagesContribute to engagement efforts with Commercial Research Organizations (CRO) in assay transfer, validation and implementation of bioanalytical & biomarker assaysEducational Requirements and QualificationsPhD in relevant field (immunology, biochemistry, biology) and post-doctoral experience in related area1-4 years of experience in cell therapy discovery/development activities in an academic or biopharmaceutical settingSkills and AbilitiesExtensive experience in PCR, q(RT)PCR and ddPCR assay development and troubleshootingKnowledge of and experience with flow cytometry is preferredKnowledge of Good Laboratory Practice (GLP) regulations is preferredUnderstanding of drug development processSpecial Skills/abilitiesAbility to manage multiple complex programs and delivery timelines concurrentlyAbility to work independently in a highly-matrixed organization to deliver on goalsExcellent verbal and written communication skillsExperience in cell therapy development

Keywords: AstraZeneca, San Francisco , AstraZeneca: Cell Therapy Bioanalytical & Biomarker Scientist, Healthcare , San Francisco, California

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