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Associate Director, Research Biology (Immunology/Translation

Company: Nektar Therapeutics
Location: San Francisco
Posted on: July 15, 2019

Job Description:

Position OverviewWe are currently seeking a highly motivated Associate Director with a focus in Immunology for our Translational Research team in our San Francisco (Mission Bay) office.This individual will focus on mechanistic pharmacology and functional biology to support late stage preclinical and Phase 1 clinical development programs. S/he will develop relevant preclinical and clinical biomarker strategies for further development in a variety of disease areas; lead and participate in the design of experiments in biological systems to characterize novel targets; and test mechanism of potential therapeutics, with emphasis on ex vivo primary models of disease.This individual will provide scientific leadership in the strategy, execution and reporting of clinical biomarker studies as well as lead technology development in the area of in vitro and ex vivo assays in the preclinical setting. Additionally, s/he interprets and communicates experimental findings and documents according to approved Nektar policy. The Associate Director will be a core member of cross-functional clinical development teams, and may manage scientists and research associates[FC1] . This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs.Additional responsibilities include:Works on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors. Exercises judgment within broadly defined practices and policies in selecting methods, techniques and evaluation criteria for obtaining results. May determine methods and procedures on new assignments.Serves as an in-house consultant.May act as spokesperson on corporate research/technology/development and advise senior management.Leads in the use of professional and scientific concepts to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways.Synthesizes multiple data sources and draws general, non-obvious conclusions. Defines complex problems, develops approaches and develops experiments with sound judgment.May independently represent the Company to outside organizations.Works in a matrix environment and interfaces with various departments, customers and partners. Puts work practices in context with larger team and participates in the implementation of change when required.Identifies needs for additional resources.May assist with designing and implementing organizational processes, budgetary and capital equipment requirements, and identifies needs for additional resources.Leads staff, provides training as needed, and ensures adherence to company policies and quality requirements.Requirements:A Bachelors/Masters degree in a scientific discipline is required; PhD in immunology, pharmaceutical sciences or closely related scientific discipline preferred. Equivalent experience may be accepted. A minimum of 10 years pharmaceutical industry experience in designing, analyzing, interpreting, and reporting pre-clinical drug development studies is required. Prior experience managing/leading a staff highly desired. We are seeking someone who is an expert in relevant experimental biology techniques including flow cytometry, cell culture, and biochemical/cell-based assays. Additional molecular biology techniques are also desirable such as qPCR, experience handling primary cells, and disease model testing. A strong immunology background is required, with immune-oncology experience a plus. We are seeking someone who maintains a broad knowledge of state-of-the-art principles and theories, and develops and analyzes new product concepts by reviewing preclinical and clinical literature.Additional requirements include:Experience working on late stage preclinical and Phase 1 clinical development teams.Ability to integrate and interpret preclinical and clinical biomarker data for successful cross-functional Interaction with Clinical Development colleagues.Ability to prepare nonclinical and clinical biomarker sections of project and regulatory documents (IND, IB, and associated regulatory documents).Working with others to write publications and make scientific presentations consistent with development strategies.Ability to work in a cross-functional drug development team environment with all levels of employees and management and the ability to lead such teams.Strong understanding of immunology and biology principles.Knowledge of advanced statistical techniques, such as data trend analysis and design of experiments, is highly desirable.Strong verbal and written communication skills are required.Ability to manage and prioritize multiple projects; communicates and relates multiple points of view to others.Demonstrated ability to work with senior management.A proven ability to develop and manage to a budget is a mustGood laboratory compliance and safety practices are a mustDemonstrated ability to develop successful relationships, internally and externallyUnderstands how to set expectations and negotiate proper milestones to track progress.At time of hire this may be individual contributor roleWe are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.

Keywords: Nektar Therapeutics, San Francisco , Associate Director, Research Biology (Immunology/Translation, Executive , San Francisco, California

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