Associate Director/ Staff Scientist, Downstream Development for Protein Development & Manufacturing
Company: Vaxcyte
Location: San Carlos
Posted on: June 26, 2022
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Job Description:
Vaxcyte, Inc. (Nasdaq: PCVX) is a vaccine innovation company
engineering high-fidelity vaccines to protect humankind from the
consequences of bacterial diseases. The Company is developing
broad-spectrum conjugate and novel protein vaccines to prevent or
treat bacterial infectious diseases. Vaxcyte's lead candidate,
VAX-24, is a 24-valent, broad-spectrum pneumococcal conjugate
vaccine being developed for the prevention of invasive pneumococcal
disease (IPD). The Company is re-engineering the way highly complex
immunizations are made through modern synthetic techniques,
including advanced chemistry and our exclusively licensed
XpressCFTM cell-free protein synthesis platform. Unlike
conventional cell-based approaches, the Company's system for
producing difficult-to-make proteins and antigens is intended to
accelerate its ability to efficiently create and deliver
high-fidelity vaccines with enhanced immunological benefits.
Vaxcyte's pipeline also includes VAX-XP, a PCV with an expanded
breadth of coverage of greater than 30 strains; VAX-A1, a
prophylactic vaccine candidate designed to prevent Group A Strep
infections; and VAX-PG, a therapeutic vaccine candidate designed to
slow or stop the progression of periodontal disease. The Company is
driven to eradicate or treat invasive bacterial infections, which
have serious and costly health consequences when left unchecked.
For more information, visit www.vaxcyte.com.Vaxcyte, headquartered
in San Carlos, CA, went public in June 2020 and currently has a
team of approximately 100 employees and anticipates continued,
significant growth. On January 6, 2022, Vaxcyte announced that the
U.S. Food and Drug Administration (FDA) had cleared the
Investigational New Drug (IND) application for VAX-24, its lead
vaccine candidate. The Company initiated the VAX-24 Phase 1/2
clinical proof-of-concept study in adults in the first quarter of
2022 and expects to announce Phase 2 topline immunogenicity,
safety, and tolerability results by the end of the year. VAX-24 was
designed to prevent IPD, which can be most serious for infants,
young children, older adults and those with immune deficiencies or
certain chronic health conditions. Given the global impact of
pneumococcal disease remains significant, the public health
community continues to advocate for vaccines that can offer broader
protection to prevent IPD. Vaxcyte's PCV franchise, consisting of
VAX-24 and VAX-XP, is designed specifically to address this need
and has the potential to deliver the broadest protection for this
very serious disease.Summary:Vaxcyte is looking for an energetic
and talented individual to join Vaxcyte's Vaccine Product
Development organization as an Associate Director/Staff Scientist
of downstream development and manufacturing within the Protein
Development and Manufacturing group.--- A dynamic leader that can
cultivate a team and develop employees while driving progress on
the pipeline.--- An exceptional team player who works seamlessly
with others, speaks up, and remains focused on achieving the best
results to achieve company goals.--- A scientific thought leader
capable of synthesizing complex biochemistry into well-designed
experiments capable of illuminating the unknown; able to plan and
utilize team strengths to execute.--- The ability to analyze and
concatenate data to draw conclusions, make clear decisions, and
communicate salient points concisely.--- A strong sense of
ownership and accountability; commitment to Vaxcyte's
mission.Essential Functions
Keywords: Vaxcyte, San Francisco , Associate Director/ Staff Scientist, Downstream Development for Protein Development & Manufacturing, Executive , San Carlos, California
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