SanFranRecruiter Since 2001
the smart solution for San Francisco jobs

Principal Scientist / Director, Cancer Biology

Company: THIRD ROCK VENTURES, LLC
Location: San Francisco
Posted on: February 25, 2021

Job Description:

Principal Scientist / Director, Cancer Biology at Relay Therapeutics Relay Therapeutics is a new breed of company at the intersection of computation and biotechnology that is committed to creating medicines that will have a transformative impact on patients. We combine unprecedented computational power with leading-edge experimental approaches across the fields of biology, biophysics, structural biology, and chemistry. This integration illuminates, for the first time, the full mobility of a protein and provides key insights into how the dynamic nature of a protein's conformation regulates function. The team at Relay is putting this principle into practice, with the aim of accelerating the development of medicines that will make a transformative difference in patients' lives. We don't just stare hard problems in the face. We go out looking for them. Are you energized by attempting to do the impossible? We're looking for you. At Relay, our team is driven by the ultimate collaboration across each of our drug discovery disciplines. Putting protein motion at the heart of drug discovery is a challenge, but we are confident that our team's dedication and urgency will create opportunities that deeply impact the lives of the patients. The Opportunity: While Relay Tx has taken the exciting step into the clinic, we are continuing to also put our energy and resources into continuing to develop cutting-edge research. We are looking for you, a future Director / Principal Scientist in Biology, to provide deep intellectual and strategical leadership as well as outstanding mentorship as we discover novel small molecule therapeutics in oncology. You will have previous success managing and fostering creativity and professional development from your group. You have a deep understanding of cancer biology and small molecule drug discovery with a broad background in cancer signaling. You have experience successfully driving oncology programs from early stages, through IND writing and towards clinical development.-- Your Role:

  • You will serve as the Biology lead on project teams passionate about developing small molecule modulators of clinically validated targets in cancer.
  • You will design and lead biology experiments to assess targets, evaluate candidate small molecules, and support drug discovery.
  • You will bring IND writing experience and driving programs towards the clinic.
  • Your in vitro--experience includes cell line profiling, pathway signaling, understanding of genomic drivers, assay development, compound profiling and progression.
  • Your in vivo--experience consists of model selection and development, tolerability, PK/PD, efficacy studies, understanding of DMPK and setting appropriate dose levels and interpretation of pharmacology data.
  • We value the strength of team development, communication and leadership that inspires motivation to drive quality research with urgency that will better patients' lives.
  • Previous experience managing reports (associates and PhD level scientists), and experience with managing external CROs--will allow our teams to keep driving fast and forward.
  • You recognize CROs as an extension of your internal team.
  • You will interpret, summarize and present research findings at internal and external scientific meetings/conferences
  • You're actively reviewing literature to bring in the newest scientific findings, ideas, and methods/technologies to impact drug discovery projects
  • Excellent communication, attitude, and interpersonal skills are essential for the success of your team and cross functional collaborations.
  • Each individual at Relay contributes to the success of the organization, and we are built on each person valuing humanity, candor, relentlessness and fearlessness.-- Your Background:
    • You earned your Ph.D. and have post-doctoral training in cancer biology with demonstrated experience in oncology small molecule drug discovery.
    • You have at least 4+ years of experience in biotech/pharma.
    • You're driven with a consistent track record of scientific excellence as reflected by high impact, peer reviewed publications and/or patents.
    • A confident and thoughtful leader with a successful track record and passion to mentor and develop your direct reports and teammates.
    • You are comfortable with - and can thrive in - an environment that is constantly changing, frequently uncertain, and where you're in charge of driving project strategies and progression.
    • You have the patience to learn from your team and peers before turning to yourself for all the answers.
    • You've got excellent communication, presentation, and inter-personal skills; your energy is infectious and motivates the team. We believe in building balanced teams and a place where our people can be their best self every day. We encourage people from underrepresented backgrounds to apply.-- Relay Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. Our Culture: At Relay Tx, we believe that along with our people, our culture is our greatest asset. In fact we're proud to share we were named as one of the Boston Business Journal's "Best Places to Work " in 2017, the--#1 place for small companies --in 2018 & the--#2 place for small companies --in 2019. To drive that culture, no one will stop you or hold you back. Instead, we will give you the tools and colleagues to push forward relentlessly and cheer you on as you go. If this resonates with you, drop us a line. About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us 29 Newbury Street
      3rd Floor
      Boston, MA 02116
      P (617) 585-2000

Keywords: THIRD ROCK VENTURES, LLC, San Francisco , Principal Scientist / Director, Cancer Biology, Executive , San Francisco, California

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Executive Jobs


Director-Information Security - IT Security CISO - Full Time - 8 Hour - Days*
Description: Director-Information Security - IT Security CISO - Full Time - 8 Hour - Days Job Description: Establishes, implements, monitors, and enforces information security policies and standards enterprise wide. (more...)
Company: John Muir Health
Location: Walnut Creek
Posted on: 03/3/2021

Chief Operating Officer
Description: Under direction of the Chief Executive Officer, the Chief Operating Officer COO is responsible for the efficiency and effectiveness of the Center's operations, devoting
Company: Petaluma Health Center
Location: Petaluma
Posted on: 03/3/2021

Retail Store Manager - Novato
Description: About Pet Food Express br br Pet Food Express is the best place to shop for pet supplies - and it's all because of the people who work here. Sure, we have better products and more convenient services. (more...)
Company: Pet Food Express
Location: Novato
Posted on: 03/3/2021


Retail Store Manager - San Rafael
Description: About Pet Food Express br br Pet Food Express is the best place to shop for pet supplies - and it's all because of the people who work here. Sure, we have better products and more convenient services. (more...)
Company: Pet Food Express
Location: San Rafael
Posted on: 03/3/2021

Social Media Manager
Description: Looking for someone who has office skills, who is willing to learn new software, and who knows how to use social media.Bilingual workers encouraged to
Company: Express Employment Professionals - San Rafael
Location: San Rafael
Posted on: 03/3/2021

Global Senior Communications Manager
Description: Who We Are br br The Communications team manages all public relations and influencer marketing for 2K titles. We are a team of talented storytellers, passionate video game players and communications (more...)
Company: 2K
Location: Novato
Posted on: 03/3/2021

Senior Compliance Manager / Compliance Manager
Description: Senior Compliance Manager / Compliance Manager At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do.--To (more...)
Company: Ultragenyx Pharmaceutical
Location: Novato
Posted on: 03/3/2021

Business Development/Sales/Account Manager- East Bay
Description: Work as a Business Development/Account Manager for a family owned industry leader. In business over 80 years, we're known for unbeatable customer service and extensive employee training and support. You'll (more...)
Company: Educational Sales
Location: Walnut Creek
Posted on: 03/3/2021

Customer Success Manager
Description: AutoRABIT is a hyper-growth SaaS software company providing a Continuous Delivery DevOps platform for SaaS technologies like Salesfore.com MuleSoft. We are located in US, India, Australia. AutoRABIT (more...)
Company: AutoRABIT
Location: San Ramon
Posted on: 03/3/2021

Sr. Director/Director, Global Medical Lead, LSD
Description: Sr. Director/Director, Global Medical Lead, LSD BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic (more...)
Company: BIOMARIN
Location: San Rafael
Posted on: 03/3/2021

Log In or Create An Account

Get the latest California jobs by following @recnetCA on Twitter!

San Francisco RSS job feeds