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Director, Facilities

Company: Vaxcyte
Location: San Carlos
Posted on: May 15, 2024

Job Description:

Company Profile:Vaxcyte, Inc. (Nasdaq: PCVX) is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Vaxcyte's lead candidate, VAX-24, is a 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine (PCV) being developed for the prevention of invasive pneumococcal disease (IPD). The Company is re-engineering the way highly complex immunizations are made through modern synthetic techniques, including advanced chemistry and our exclusively licensed XpressCFTM cell-free protein synthesis platform. Unlike conventional cell-based approaches, the Company's system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to efficiently create and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte's pipeline also includes VAX-31, a 31-valent PCV candidate; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine program designed to prevent Shigella. The Company is driven to eradicate or treat invasive bacterial infections, which have serious and costly health consequences when left unchecked. For more information, visit .Vaxcyte, headquartered in San Carlos, CA, went public in June 2020 and currently has a team of approximately 180 employees and anticipates continued, significant growth. Following equity offerings in October 2022 and April 2023, which generated over $1.1 billion in net proceeds, the Company's balance sheet is further strengthened to advance its pipeline of novel vaccines, including VAX-24. These financings followed positive data readouts from Vaxcyte's Phase 1/2 proof-of-concept study evaluating VAX-24 in adults aged 18-64 and Phase 2 study in adults 65 and older. The Company believes these results support a best-in-class potential for VAX-24, which was designed to replace the current standard-of-care in adults and children. VAX-24 is being investigated for the prevention of IPD, which can be most serious for infants, young children, older adults and those with immune deficiencies or certain chronic health conditions. Given the global impact of pneumococcal disease remains significant, the public health community continues to advocate for vaccines that can offer broader protection to prevent IPD. Vaxcyte's PCV franchise, consisting of VAX-24 and VAX-31, is designed specifically to address this need and has the potential to deliver the broadest protection for this very serious disease. We believe that our PCVs could receive regulatory approval based on successful completion of clinical studies utilizing well-defined surrogate immune endpoints, consistent with how other PCVs have obtained regulatory approval in the past, rather than requiring clinical field efficacy studies.Summary:Vaxcyte is looking for an energetic and talented individual to join Vaxcyte's Facilities organization. The primary function of this Associate Director/Director-level position is to lead Facilities operations and site services for Vaxcyte's Headquarters. This position will manage and grow a high-performing and service-centric team comprised of full-time employees, contingent workers and 3rd party partners. Beyond functional and technical experience, primary keys to success for this role focus on relationships, culture, trust, forward thought, and operational excellence. This position reports to the Senior Director Facilities.Note: rotational, shared 24x7 on-call support is required of this role.Essential Functions:

  • Partner closely with the Director of Lab Operations to establish, monitor and maintain the labs and all lab equipment.
  • Support planning oversight for the installation of lab equipment.
  • Help cultivate a culture of compliance with job-appropriate policies, procedures and training.
  • Collaborate, develop and evolve a rolling 3-5 year strategic Facilities roadmap for Vaxcyte's HQ and associated spaces.
  • Plan and co-lead relocations, expansions and redesign initiatives.
  • Oversee ongoing space planning and assignment move/add/change efforts.
  • Manage site functions as assigned.
  • Establish and maintain 24x7 on-call schedule, site lead roster and emergency call tree for Facilities team.
  • Help drive key processes and systems related to Facility operations to ensure they are integrated and monitored.
  • Maintain master calendar for required inspections, preventative maintenance, submissions, renewals, and (re)certifications via Facilities Computerized Maintenance Management System (CMMS). CMMS will be the master database for the general facilities including the Labs and lab equipment.
  • Establish and operationalize strategic relationships with key external partners.
  • Lead, coach and manage a high-performing Facilities team with a focus on career growth.
  • Help nurture and grow workplace engagement through creative Facilities solutions.
  • Liaise regularly with property managers, external agencies and key 3rd party partners.
  • Engage regularly with employees and business partners to forge relationships and build trust.
  • Operationalize and/or automate Facilities functions for improved consistency and efficiency.
  • Support the development of procedures that comply with appropriate cGxP and other statutory requirements.
  • Manage Vaxcyte HQ Facilities projects and serve as SME for cross-functional and enterprise initiatives.
  • Establish functional KPI's and report regularly on performance against metric/measure targets.
  • Create a customer-centric Facilities support capability built upon solid process and technology.
  • Work with IT and business partners to identify, implement and evolve Facilities systems.
  • Partner closely with Finance to establish, monitor and maintain Facilities budgets.
  • Plan, oversee and track Facilities-related procurement; help optimize procurement process.
  • Serve as Facilities SME and point of contact during audits.
  • Assist with Vaxcyte's emergency and continuity planning with ongoing table-top exercises.
  • Support troubleshooting and perform minor repairs in office and laboratory settings.
  • Member of Emergency Response Team.Requirements:
    • BS in Engineering or similar technical-related degree.
    • 8+ years' Facilities experience in the life sciences industry, biotech preferred.
    • 5+ years' people-management experience.
    • Project management experience with office and lab builds; manufacturing a plus.
    • Expert-level proficiency with facilities and lab systems such as BMS, CMMS, ELN/LIMS.
    • Proficient, hands-on experience with biotech facility and laboratory instruments and equipment.
    • Relentless focus and passion around process improvements (efficiency and automation).
    • Fluent in Facilities-related statutory/regulatory requirements for a public life sciences company.
    • Proficiency developing and managing corporate EH&S programs.
    • Practical experience with system/equipment qualification plans and protocols.
    • Ability to thrive in a highly-dynamic and fluid environment where priorities may quickly change.
    • Excellent communication, customer service and relationship skills are an absolute must.
    • All Vaxcyte employees require vaccination against COVID-19.Reports to: Senior Director, FacilitiesLocation: San Carlos, CACompensation:The compensation package will be competitive and includes comprehensive benefits and an equity component.Salary Range: $215,000 - $228,000Send resumes to: Vaxcyte, Inc. 825 Industrial Road, Suite 300San Carlos, CA 94070We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion,sex, sexual orientation, gender identity, national origin, disability or veteran status.

Keywords: Vaxcyte, San Francisco , Director, Facilities, Accounting, Auditing , San Carlos, California

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